Phenotypic diversification by enhanced genome restructuring after induction of multiple DNA double-strand breaks

DNA double-strand break (DSB)-mediated genome rearrangements are assumed to provide diverse raw genetic materials enabling accelerated adaptive evolution; however, it remains unclear about the consequences of massive simultaneous DSB formation in cells and their resulting phenotypic impact. Here, we...

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Detalles Bibliográficos
Autores principales: Muramoto, Nobuhiko, Oda, Arisa, Tanaka, Hidenori, Nakamura, Takahiro, Kugou, Kazuto, Suda, Kazuki, Kobayashi, Aki, Yoneda, Shiori, Ikeuchi, Akinori, Sugimoto, Hiroki, Kondo, Satoshi, Ohto, Chikara, Shibata, Takehiko, Mitsukawa, Norihiro, Ohta, Kunihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959919/
https://www.ncbi.nlm.nih.gov/pubmed/29777105
http://dx.doi.org/10.1038/s41467-018-04256-y

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