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Functional Proteomic Profiling of Secreted Serine Proteases in Health and Inflammatory Bowel Disease

While proteases are essential in gastrointestinal physiology, accumulating evidence indicates that dysregulated proteolysis plays a pivotal role in the pathophysiology of inflammatory bowel disease (IBD). Nonetheless, the identity of overactive proteases released by human colonic mucosa remains larg...

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Detalles Bibliográficos
Autores principales: Denadai-Souza, Alexandre, Bonnart, Chrystelle, Tapias, Núria Solà, Marcellin, Marlène, Gilmore, Brendan, Alric, Laurent, Bonnet, Delphine, Burlet-Schiltz, Odile, Hollenberg, Morley D., Vergnolle, Nathalie, Deraison, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959920/
https://www.ncbi.nlm.nih.gov/pubmed/29777136
http://dx.doi.org/10.1038/s41598-018-26282-y