Methyl-donor depletion of head and neck cancer cells in vitro establishes a less aggressive tumour cell phenotype

PURPOSE: DNA methylation plays a fundamental role in the epigenetic control of carcinogenesis and is, in part, influenced by the availability of methyl donors obtained from the diet. In this study, we developed an in-vitro model to investigate whether methyl donor depletion affects the phenotype and...

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Detalles Bibliográficos
Autores principales: Hearnden, Vanessa, Powers, Hilary J., Elmogassabi, Abeir, Lowe, Rosanna, Murdoch, Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959985/
https://www.ncbi.nlm.nih.gov/pubmed/28251343
http://dx.doi.org/10.1007/s00394-017-1411-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959985/
https://www.ncbi.nlm.nih.gov/pubmed/28251343
http://dx.doi.org/10.1007/s00394-017-1411-5

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