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Methyl-donor depletion of head and neck cancer cells in vitro establishes a less aggressive tumour cell phenotype
PURPOSE: DNA methylation plays a fundamental role in the epigenetic control of carcinogenesis and is, in part, influenced by the availability of methyl donors obtained from the diet. In this study, we developed an in-vitro model to investigate whether methyl donor depletion affects the phenotype and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5959985/ https://www.ncbi.nlm.nih.gov/pubmed/28251343 http://dx.doi.org/10.1007/s00394-017-1411-5 |