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Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3

BACKGROUND: Microglial polarization with M1/M2 phenotype shifts and the subsequent neuroinflammatory responses are vital contributing factors for spinal cord injury (SCI)-induced secondary injury. Nuclear factor-κB (NF-κB) is considered the central transcription factor of inflammatory mediators, whi...

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Detalles Bibliográficos
Autores principales:	Chen, Shoubo, Ye, Jingfang, Chen, Xiangrong, Shi, Jinnan, Wu, Wenhua, Lin, Wenping, Lin, Weibin, Li, Yasong, Fu, Huangde, Li, Shun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960086/ https://www.ncbi.nlm.nih.gov/pubmed/29776446 http://dx.doi.org/10.1186/s12974-018-1193-6

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