Myeloid-specific TAK1 deletion results in reduced brain monocyte infiltration and improved outcomes after stroke

BACKGROUND: Activation of transforming growth factor-β-activated kinase 1 (TAK1) occurs after stroke and leads to an exacerbation of brain injury. TAK1 is involved in innate and adaptive immune responses, but it has divergent inflammatory effects that are dependent on the cell type in which it is ac...

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Detalles Bibliográficos
Autores principales: Chauhan, Anjali, Hudobenko, Jacob, Al Mamun, Abdullah, Koellhoffer, Edward C., Patrizz, Anthony, Ritzel, Rodney M., Ganesh, Bhanu P., McCullough, Louise D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960093/
https://www.ncbi.nlm.nih.gov/pubmed/29776451
http://dx.doi.org/10.1186/s12974-018-1188-3

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