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Establishing an innovative carbohydrate metabolic pathway for efficient production of 2-keto-l-gulonic acid in Ketogulonicigenium robustum initiated by intronic promoters

BACKGROUND: 2-Keto-l-gulonic acid (2-KGA), the precursor of vitamin C, is currently produced by two-step fermentation. In the second step, l-sorbose is transformed into 2-KGA by the symbiosis system composed of Ketogulonicigenium vulgare and Bacillus megaterium. Due to the different nutrient require...

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Detalles Bibliográficos
Autores principales:	Wang, Cai-Yun, Li, Ye, Gao, Zi-Wei, Liu, Li-Cheng, Zhang, Meng-Yue, Zhang, Tian-Yuan, Wu, Chun-Fu, Zhang, Yi-Xuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960096/ https://www.ncbi.nlm.nih.gov/pubmed/29778095 http://dx.doi.org/10.1186/s12934-018-0932-9

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