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Metabolic therapy with PEG-arginase induces a sustained complete remission in immunotherapy-resistant melanoma

BACKGROUND: Metastatic melanoma is an aggressive skin cancer with a poor prognosis. Current treatment strategies for high-stage melanoma are based around the use of immunotherapy with immune checkpoint inhibitors such as anti-PDL1 or anti-CTLA4 antibodies to stimulate anti-cancer T cell responses, y...

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Detalles Bibliográficos
Autores principales:	De Santo, Carmela, Cheng, Paul, Beggs, Andrew, Egan, Sharon, Bessudo, Alberto, Mussai, Francis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960181/ https://www.ncbi.nlm.nih.gov/pubmed/29776373 http://dx.doi.org/10.1186/s13045-018-0612-6

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