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Postnatal relative adrenal insufficiency results in methylation of the glucocorticoid receptor gene in preterm infants: a retrospective cohort study
BACKGROUND: To investigate the relationship between early-life stress and glucocorticoid receptor (GR) gene methylation, which may result in long-lasting neurodevelopmental impairment, we performed a longitudinal analysis of the methylation ratio within the GR gene promoter 1F region using next-gene...
Autores principales: | Kantake, Masato, Ohkawa, Natsuki, Iwasaki, Tomohiro, Ikeda, Naho, Awaji, Atsuko, Saito, Nobutomo, Shoji, Hiromichi, Shimizu, Toshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960186/ https://www.ncbi.nlm.nih.gov/pubmed/29796117 http://dx.doi.org/10.1186/s13148-018-0497-9 |
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