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Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-thir...

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Detalles Bibliográficos
Autores principales: del Valle-Mendoza, Juana, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel, del Valle-Vargas, Cristina, Cieza-Mora, Erico, Martins-Luna, Johanna, Aquino-Ortega, Ronald, Silva-Vásquez, Andrea, Bazán-Mayra, Jorge, Weilg, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960213/
https://www.ncbi.nlm.nih.gov/pubmed/29776433
http://dx.doi.org/10.1186/s13104-018-3405-7
Descripción
Sumario:OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3405-7) contains supplementary material, which is available to authorized users.