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Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts

OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-thir...

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Autores principales: del Valle-Mendoza, Juana, Silva-Caso, Wilmer, Aguilar-Luis, Miguel Angel, del Valle-Vargas, Cristina, Cieza-Mora, Erico, Martins-Luna, Johanna, Aquino-Ortega, Ronald, Silva-Vásquez, Andrea, Bazán-Mayra, Jorge, Weilg, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960213/
https://www.ncbi.nlm.nih.gov/pubmed/29776433
http://dx.doi.org/10.1186/s13104-018-3405-7
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author del Valle-Mendoza, Juana
Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
author_facet del Valle-Mendoza, Juana
Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
author_sort del Valle-Mendoza, Juana
collection PubMed
description OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3405-7) contains supplementary material, which is available to authorized users.
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spelling pubmed-59602132018-05-24 Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts del Valle-Mendoza, Juana Silva-Caso, Wilmer Aguilar-Luis, Miguel Angel del Valle-Vargas, Cristina Cieza-Mora, Erico Martins-Luna, Johanna Aquino-Ortega, Ronald Silva-Vásquez, Andrea Bazán-Mayra, Jorge Weilg, Pablo BMC Res Notes Research Note OBJECTIVE: Describe the prevalence of Bordetella pertussis via PCR in children under 5 years old hospitalized as probable cases of pertussis and report the most common clinical features among them. RESULTS: A positive PCR result for B. pertussis was observed in 20.5% of our samples (18/88), one-third of them were from infants between 2 and 3 months old. The most common symptoms were paroxysms of coughing (88.9%), difficulty breathing (72.2%), cyanosis (77.8%) and fever (50%). The mother was the most common symptomatic carrier (27.8%), followed by uncles/aunts (22.2%) among children with pertussis. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-3405-7) contains supplementary material, which is available to authorized users. BioMed Central 2018-05-18 /pmc/articles/PMC5960213/ /pubmed/29776433 http://dx.doi.org/10.1186/s13104-018-3405-7 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Note
del Valle-Mendoza, Juana
Silva-Caso, Wilmer
Aguilar-Luis, Miguel Angel
del Valle-Vargas, Cristina
Cieza-Mora, Erico
Martins-Luna, Johanna
Aquino-Ortega, Ronald
Silva-Vásquez, Andrea
Bazán-Mayra, Jorge
Weilg, Pablo
Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_full Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_fullStr Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_full_unstemmed Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_short Bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
title_sort bordetella pertussis in children hospitalized with a respiratory infection: clinical characteristics and pathogen detection in household contacts
topic Research Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960213/
https://www.ncbi.nlm.nih.gov/pubmed/29776433
http://dx.doi.org/10.1186/s13104-018-3405-7
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