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Debate: The slippery slope of surrogate outcomes
Surrogate outcomes are frequently used in cardiovascular disease research. A concern is that changes in surrogate markers may not reflect changes in disease outcomes. Two recent clinical trials (Heart and Estrogen/Progestin Replacement Study [HERS], and the Antihypertensive and Lipid-Lowering Treatm...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC59603/ https://www.ncbi.nlm.nih.gov/pubmed/11714414 http://dx.doi.org/10.1186/cvm-1-2-076 |