Reactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis

Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...

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Detalles Bibliográficos
Autores principales: Carvalho, Lina, Gomes, Joana R. M., Tavares, Ludgero C., Xavier, Ana R., Klika, Karel D., Holmdahl, Rikard, Carvalho, Rui A., Souto-Carneiro, M. Margarida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960697/
https://www.ncbi.nlm.nih.gov/pubmed/29867918
http://dx.doi.org/10.3389/fimmu.2018.00701

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