Tespa1 Deficiency Dampens Thymus-Dependent B-Cell Activation and Attenuates Collagen-Induced Arthritis in Mice

Thymocyte-expressed, positive selection-associated 1 (Tespa1) plays an important role in both T cell receptor (TCR)-driven thymocyte development and in the FcεRI-mediated activation of mast cells. Herein, we show that lack of Tespa1 does not impair B cell development but dampens the in vitro activat...

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Detalles Bibliográficos
Autores principales: Yao, Yunliang, Huang, Wei, Li, Xiaoyu, Li, Xiawei, Qian, Jin, Han, Hui, Sun, Hui, An, Xiangli, Lu, Linrong, Zhao, Hongxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960706/
https://www.ncbi.nlm.nih.gov/pubmed/29867947
http://dx.doi.org/10.3389/fimmu.2018.00965

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