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Pharmacogenetic Aspects of the Interaction of AT1 Receptor Antagonists With ATP-Binding Cassette Transporter ABCG2

The ATP-binding cassette transporter ABCG2 (BCRP and MXR) is involved in the absorption, distribution, and elimination of numerous drugs. Thus, drugs that are able to reduce the activity of ABCG2, e.g., antihypertensive AT1 receptor antagonists (ARBs), may cause drug-drug interactions and compromise...

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Detalles Bibliográficos
Autores principales:	Ripperger, Anne, Krischer, Anna, Robaa, Dina, Sippl, Wolfgang, Benndorf, Ralf A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960723/ https://www.ncbi.nlm.nih.gov/pubmed/29867471 http://dx.doi.org/10.3389/fphar.2018.00463

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