The Ontogeny of Cytochrome P450 Enzyme Activity and Protein Abundance in Conventional Pigs in Support of Preclinical Pediatric Drug Research

Since the implementation of several legislations to improve pediatric drug research, more pediatric clinical trials are being performed. In order to optimize these pediatric trials, adequate preclinical data are necessary, which are usually obtained by juvenile animal models. The growing piglet has...

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Detalles Bibliográficos
Autores principales: Millecam, Joske, De Clerck, Laura, Govaert, Elisabeth, Devreese, Mathias, Gasthuys, Elke, Schelstraete, Wim, Deforce, Dieter, De Bock, Lies, Van Bocxlaer, Jan, Sys, Stanislas, Croubels, Siska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960725/
https://www.ncbi.nlm.nih.gov/pubmed/29867477
http://dx.doi.org/10.3389/fphar.2018.00470

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