Cargando…
The Mechanisms of Action of Ribosome-Targeting Peptide Antibiotics
The ribosome is one of the major targets in the cell for clinically used antibiotics. However, the increase in multidrug resistant bacteria is rapidly reducing the effectiveness of our current arsenal of ribosome-targeting antibiotics, highlighting the need for the discovery of compounds with new sc...
Autores principales: | Polikanov, Yury S., Aleksashin, Nikolay A., Beckert, Bertrand, Wilson, Daniel N. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960728/ https://www.ncbi.nlm.nih.gov/pubmed/29868608 http://dx.doi.org/10.3389/fmolb.2018.00048 |
Ejemplares similares
-
Therapeutic Peptides Targeting PPI in Clinical Development: Overview, Mechanism of Action and Perspectives
por: Cabri, Walter, et al.
Publicado: (2021) -
Peptides Targeting the Interaction Between Erb1 and Ytm1 Ribosome Assembly Factors
por: Orea-Ordóñez, Lidia, et al.
Publicado: (2021) -
Exploring Amyloidogenicity of Peptides From Ribosomal S1 Protein to Develop Novel AMPs
por: Galzitskaya, Oxana V.
Publicado: (2021) -
Repurposing Modular Polyketide Synthases and Non-ribosomal Peptide Synthetases for Novel Chemical Biosynthesis
por: Hwang, Soonkyu, et al.
Publicado: (2020) -
Functional Sites of Ribosome Modulation Factor (RMF) Involved in the Formation of 100S Ribosome
por: Yoshida, Hideji, et al.
Publicado: (2021)