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Effects of salidroside on rat CYP enzymes by a cocktail of probe drugs

OBJECTIVE(S): In this study, we aimed to evaluate the effect of salidroside on the activities of the different drug-metabolizing enzymes CYP1A2, CYP2B6, CYP2C9, CYP2D6 and CYP3A4 in rats, in which a specific probe drug was used for each enzyme. MATERIALS AND METHODS: After pretreatment with salidros...

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Detalles Bibliográficos
Autores principales: Wei, Yan-Li, Du, Hong-Jian, Lin, Yi-Ping, Wu, Mei-Ling, Xu, Ren-ai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960761/
https://www.ncbi.nlm.nih.gov/pubmed/29796228
http://dx.doi.org/10.22038/IJBMS.2018.26106.6414

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