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Effects of salidroside on rat CYP enzymes by a cocktail of probe drugs
OBJECTIVE(S): In this study, we aimed to evaluate the effect of salidroside on the activities of the different drug-metabolizing enzymes CYP1A2, CYP2B6, CYP2C9, CYP2D6 and CYP3A4 in rats, in which a specific probe drug was used for each enzyme. MATERIALS AND METHODS: After pretreatment with salidros...
Autores principales: | Wei, Yan-Li, Du, Hong-Jian, Lin, Yi-Ping, Wu, Mei-Ling, Xu, Ren-ai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mashhad University of Medical Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5960761/ https://www.ncbi.nlm.nih.gov/pubmed/29796228 http://dx.doi.org/10.22038/IJBMS.2018.26106.6414 |
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