Cargando…

Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin’s lymphoma

BACKGROUND: This two-stage, phase IIa study investigated the antitumor activity and safety of MOR208, an Fc-engineered, humanized, CD19 antibody, in patients with relapsed or refractory (R-R) B-cell non-Hodgkin’s lymphoma (NHL). CD19 is broadly expressed across the B-lymphocyte lineage, including in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jurczak, W, Zinzani, P L, Gaidano, G, Goy, A, Provencio, M, Nagy, Z, Robak, T, Maddocks, K, Buske, C, Ambarkhane, S, Winderlich, M, Dirnberger-Hertweck, M, Korolkiewicz, R, Blum, K A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961010/ https://www.ncbi.nlm.nih.gov/pubmed/29444231 http://dx.doi.org/10.1093/annonc/mdy056

Ejemplares similares

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma
por: Duell, Johannes, et al.
Publicado: (2021)

Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis
por: Constantinescu, Cris S., et al.
Publicado: (2015)

A phase 2a, single‐arm, open‐label study of tafasitamab, a humanized, Fc‐modified, anti‐CD19 antibody, in patients with relapsed/refractory B‐precursor cell acute lymphoblastic leukemia
por: Klisovic, Rebecca B., et al.
Publicado: (2021)

Single-agent MOR208 salvage and maintenance therapy in a patient with refractory/relapsing diffuse large B-cell lymphoma: a case report
por: Jurczak, Wojciech, et al.
Publicado: (2016)

MOR103, a human monoclonal antibody to granulocyte–macrophage colony-stimulating factor, in the treatment of patients with moderate rheumatoid arthritis: results of a phase Ib/IIa randomised, double-blind, placebo-controlled, dose-escalation trial
por: Behrens, Frank, et al.
Publicado: (2015)

Zacualpan, Mor. : un estudio de relaciones sociales
por: Ramírez Melgarejo, Ramón
Publicado: (1976)

Mors repentina, ensayos sobre la grandeza y la miseria del cuerpo /
por: González-Crussí, F.
Publicado: (2001)

Theoretical Study for Adsorption–Diffusion on H-MOR and Pyridine Pre-adsorbed H-MOR of Dimethyl Ether Carbonylation
por: Zhao, Jiabao, et al.
Publicado: (2023)

Role of efficacy as a determinant of locomotor activation by mu‐opioid receptor (MOR) ligands in female and male mice. II. Effects of novel MOR‐selective phenylmorphans with high‐to‐low MOR efficacy
por: Santos, Edna J., et al.
Publicado: (2023)

Directed Flow in 158 A GeV $^{208}Pb$ + $^{208}Pb$ Collisions
por: Aggarwal, M.M., et al.
Publicado: (1998)

Plume–MOR decoupling and the timing of India–Eurasia collision
por: Sehsah, Haytham, et al.
Publicado: (2022)

Freeze-Out Parameters in Central 158 AGeV $^{208}Pb$ + $^{208}Pb$ Collisions
por: Aggarwal, M.M., et al.
Publicado: (1999)

Direct Photon Production in 158 A GeV $^{208}Pb+^{208}Pb$ collisions
por: Aggarwal, M.M., et al.
Publicado: (2001)

Beyond Mor: Can Induction of Dopamine Homeostasis Along with Electrotherapy Attenuate the Opioid Crisis?
por: Blum, Kenneth, et al.
Publicado: (2023)

Interferometry of direct photons in central $^{208}$Pb+$^{208}$Pb collisions at 158A GeV
por: Aggarwal, M M, et al.
Publicado: (2004)

Observation of Direct Photons in Central 158 A GeV $^{208}Pb+^{208}Pb$ Collisions
por: Aggarwal, M.M., et al.
Publicado: (2000)

$\Delta^{++}$ production in 158 A GeV $^{208}Pb+^{208}Pb$ interactions at the CERN SPS
por: Aggarwal, M M, et al.
Publicado: (2000)

RVX 208
Publicado: (2012)

Scaling of Particle and Transverse Energy Production in 208Pb+208Pb collisions at 158 A GeV
por: Aggarwal, M.M., et al.
Publicado: (2001)

Centrality Dependence of Neutral Pion Production in 158 A GeV $^{208}Pb +^{208}Pb$ Collisions
por: Aggarwal, M.M., et al.
Publicado: (1998)

Diferencía social, estudio de caso: Jaloxtoc, Mor.
por: Trujillo Santiesteban, María de Lourdes
Publicado: (1988)

Measurement of conversion electrons with the $^{208}Pb(p,n)^{208}Bi$ reaction and derivation of the shell model proton neutron hole interaction from the properties of $^{208}Bi$
por: Maier, K H, et al.
Publicado: (2007)

Compton scattering on $^{208}$Pb
por: Alberico, W M, et al.
Publicado: (1982)

Competition between Allowed and First-Forbidden $β$ Decay: The Case of $^{208}$Hg$→^{208}$Tl
por: Carroll, R J, et al.
Publicado: (2020)

Competition between allowed and first-forbidden $β$ decays of $^{208}$At and expansion of the $^{208}$Po level scheme
por: Brunet, M, et al.
Publicado: (2021)

Commentary on: “Does caffeine enhance bowel recovery after elective colorectal resection? A prospective double-blinded randomized clinical trial” Tech Coloproctol. 2021 Apr 26. doi: 10.1007/s10151-021-02450-7
por: Korolkiewicz, P. K.
Publicado: (2021)

Synthesis of Hierarchical MOR-Type Zeolites with Improved Catalytic Properties
por: Mcheik, Zeinab, et al.
Publicado: (2021)

MOR promotes epithelial-mesenchymal transition and proliferation via PI3K/AKT signaling pathway in human colorectal cancer: MOR promotes EMT and proliferation
por: Gao, Lingling, et al.
Publicado: (2022)

Cantata no. 208 Was mir behagt : Hunt cantata /
por: Bach, Johann Sebastian, 1685-1750
Publicado: (1986)

Particle production in 158.A GeV $^{208}$Pb + $^{208}$Pb collisions
por: Awes, T C
Publicado: (1999)

Deep annotation of mouse iso-miR and iso-moR variation
por: Zhou, Hongjun, et al.
Publicado: (2012)

Informing radiotherapy decisions in stage I/IIa Hodgkin lymphoma: modeling life expectancy using radiation dosimetry
por: Jones, David A., et al.
Publicado: (2022)

RE-MIND: Comparing Tafasitamab + Lenalidomide (L-MIND) with a Real-world Lenalidomide Monotherapy Cohort in Relapsed or Refractory Diffuse Large B-cell Lymphoma
por: Zinzani, Pier Luigi, et al.
Publicado: (2021)

Oral Presentations 208–237
Publicado: (2001)

Direct Photon Production in 158 A GeV $^{208}$ PB+$^{208}$ PB Collisions
por: Peitzmann, Thomas
Publicado: (2001)

Two-phonon giant dipole resonance in $^{208}$Pb
por: Boretzky, K, et al.
Publicado: (1996)

Transient effects in proton induced fission of 208Pb
por: Ayyad, Y, et al.
Publicado: (2012)

Improved Efficacy of Tafasitamab plus Lenalidomide versus Systemic Therapies for Relapsed/Refractory DLBCL: RE-MIND2, an Observational Retrospective Matched Cohort Study
por: Nowakowski, Grzegorz S., et al.
Publicado: (2022)

Electromagnetic Dissociation of Target Nuclei by $^{208}$Pb Projectiles
por: Fadem, B, et al.
Publicado: (2002)

Regulation of mammalian MOR-1 gene expression after chronic treatment with morphine
por: PRENUS, ROSE V., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_7klm703fso25q3lpv5162nst4n