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Chromatin assembly factor-1 (CAF-1) chaperone regulates Cse4 deposition into chromatin in budding yeast

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Correct localization of the centromeric histone variant CenH3/CENP-A/Cse4 is an important part of faithful chromosome segregation. Mislocalization of CenH3 could affect chromosome segregation, DNA replication and transcription. CENP-A is often overexpressed and mislocalized in cancer genomes, but th...

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Detalles Bibliográficos
Autores principales:	Hewawasam, Geetha S, Dhatchinamoorthy, Karthik, Mattingly, Mark, Seidel, Chris, Gerton, Jennifer L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Gene regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961020/ https://www.ncbi.nlm.nih.gov/pubmed/29522205 http://dx.doi.org/10.1093/nar/gky169

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