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Targeting the human epidermal growth factor receptor 2 (HER2) oncogene in colorectal cancer
Human epidermal growth factor receptor 2 (HER2) is an oncogenic driver, and a well-established therapeutic target in breast and gastric cancers. Using functional and genomic analyses of patient-derived xenografts, we previously showed that a subset (approximately 5%) of metastatic colorectal cancer...
Autores principales: | Siena, S, Sartore-Bianchi, A, Marsoni, S, Hurwitz, H I, McCall, S J, Penault-Llorca, F, Srock, S, Bardelli, A, Trusolino, L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961091/ https://www.ncbi.nlm.nih.gov/pubmed/29659677 http://dx.doi.org/10.1093/annonc/mdy100 |
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