Protein-mediated loops in supercoiled DNA create large topological domains

Supercoiling can alter the form and base pairing of the double helix and directly impact protein binding. More indirectly, changes in protein binding and the stress of supercoiling also influence the thermodynamic stability of regulatory, protein-mediated loops and shift the equilibria of fundamenta...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Ding, Yue, Leng, Fenfei, Dunlap, David, Finzi, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961096/
https://www.ncbi.nlm.nih.gov/pubmed/29538766
http://dx.doi.org/10.1093/nar/gky153

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961096/
https://www.ncbi.nlm.nih.gov/pubmed/29538766
http://dx.doi.org/10.1093/nar/gky153

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