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Altered brain morphology after focal radiation reveals impact of off-target effects: implications for white matter development and neurogenesis

BACKGROUND: Children with brain tumors treated with cranial radiation therapy (RT) often exhibit cognitive late effects, commonly associated with reduced white matter (WM) volume and decreased neurogenesis. The impact of radiation damage in particular regions or tissues on brain development as a who...

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Detalles Bibliográficos
Autores principales: Beera, Kiran G, Li, Yu-Qing, Dazai, Jun, Stewart, James, Egan, Shannon, Ahmed, Mashal, Wong, C Shun, Jaffray, David A, Nieman, Brian J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961122/
https://www.ncbi.nlm.nih.gov/pubmed/29228390
http://dx.doi.org/10.1093/neuonc/nox211