Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells

Reactive oxygen species (ROS) are a byproduct of cell metabolism, and can also arise from environmental sources, such as toxins or radiation. Depending on dose and context, ROS have both beneficial and deleterious roles in mammalian development and disease, therefore it is crucial to understand how...

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Detalles Bibliográficos
Autores principales: Miotto, Benoit, Marchal, Claire, Adelmant, Guillaume, Guinot, Nadège, Xie, Ping, Marto, Jarrod A, Zhang, Lingqiang, Defossez, Pierre-Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961141/
https://www.ncbi.nlm.nih.gov/pubmed/29490077
http://dx.doi.org/10.1093/nar/gky149

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