Cargando…

RNA-splicing factor SART3 regulates translesion DNA synthesis

Translesion DNA synthesis (TLS) is one mode of DNA damage tolerance that uses specialized DNA polymerases to replicate damaged DNA. DNA polymerase η (Polη) is well known to facilitate TLS across ultraviolet (UV) irradiation and mutations in POLH are implicated in skin carcinogenesis. However, the ba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Min, Zhou, Bo, Gong, Juanjuan, Xing, Lingyu, Ma, Xiaolu, Wang, Fengli, Wu, Wei, Shen, Hongyan, Sun, Chenyi, Zhu, Xuefei, Yang, Yeran, Sun, Yazhou, Liu, Yang, Tang, Tie-Shan, Guo, Caixia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961147/ https://www.ncbi.nlm.nih.gov/pubmed/29590477 http://dx.doi.org/10.1093/nar/gky220

Ejemplares similares

Mismatch repair protein MSH2 regulates translesion DNA synthesis following exposure of cells to UV radiation
por: Lv, Lingna, et al.
Publicado: (2013)

Ataxin-3 promotes genome integrity by stabilizing Chk1
por: Tu, Yingfeng, et al.
Publicado: (2017)

RBM45 competes with HDAC1 for binding to FUS in response to DNA damage
por: Gong, Juanjuan, et al.
Publicado: (2017)

Translesion-synthesis DNA polymerases participate in replication of the telomeres in Streptomyces
por: Tsai, Hsiu-Hui, et al.
Publicado: (2012)

Inhibition of translesion DNA polymerase by archaeal reverse gyrase
por: Valenti, Anna, et al.
Publicado: (2009)

FANCD2 and REV1 cooperate in the protection of nascent DNA strands in response to replication stress
por: Yang, Yeran, et al.
Publicado: (2015)

In vivo evidence for translesion synthesis by the replicative DNA polymerase δ
por: Hirota, Kouji, et al.
Publicado: (2016)

Translesion synthesis of O(4)-alkylthymidine lesions in human cells
por: Wu, Jun, et al.
Publicado: (2016)

Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases
por: Ho, The Vinh, et al.
Publicado: (2011)

PCNA tool belts and polymerase bridges form during translesion synthesis
por: Boehm, Elizabeth M., et al.
Publicado: (2016)

Regulation of error-prone translesion synthesis by Spartan/C1orf124
por: Kim, Myoung Shin, et al.
Publicado: (2013)

A defect in homologous recombination leads to increased translesion synthesis in E. coli
por: Naiman, Karel, et al.
Publicado: (2016)

Eukaryotic stress–induced mutagenesis is limited by a local control of translesion synthesis
por: Masłowska, Katarzyna H, et al.
Publicado: (2022)

Beyond translesion synthesis: polymerase κ fidelity as a potential determinant of microsatellite stability
por: Hile, Suzanne E., et al.
Publicado: (2012)

Translesion synthesis mechanisms depend on the nature of DNA damage in UV-irradiated human cells
por: Quinet, Annabel, et al.
Publicado: (2016)

Characterization of a coupled DNA replication and translesion synthesis polymerase supraholoenzyme from archaea
por: Cranford, Matthew T., et al.
Publicado: (2017)

Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos
por: Lo Furno, Elena, et al.
Publicado: (2021)

Constitutive fusion of ubiquitin to PCNA provides DNA damage tolerance independent of translesion polymerase activities
por: Pastushok, Landon, et al.
Publicado: (2010)

A non-catalytic role of RecBCD in homology directed gap repair and translesion synthesis
por: Laureti, Luisa, et al.
Publicado: (2017)

Sustained pigmentation causes DNA damage and invokes translesion polymerase Polκ for repair in melanocytes
por: Ghazi, Madeeha, et al.
Publicado: (2023)

Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1
por: Xu, Xin, et al.
Publicado: (2016)

Ribonucleotide incorporation by human DNA polymerase η impacts translesion synthesis and RNase H2 activity
por: Mentegari, Elisa, et al.
Publicado: (2017)

The POLD3 subunit of DNA polymerase δ can promote translesion synthesis independently of DNA polymerase ζ
por: Hirota, Kouji, et al.
Publicado: (2015)

REV1 restrains DNA polymerase ζ to ensure frame fidelity during translesion synthesis of UV photoproducts in vivo
por: Szüts, Dávid, et al.
Publicado: (2008)

Role of the ubiquitin-binding domain of Polη in Rad18-independent translesion DNA synthesis in human cell extracts
por: Schmutz, Valérie, et al.
Publicado: (2010)

Predominant role of DNA polymerase eta and p53-dependent translesion synthesis in the survival of ultraviolet-irradiated human cells
por: Lerner, Leticia K., et al.
Publicado: (2017)

Recombinase and translesion DNA polymerase decrease the speed of replication fork progression during the DNA damage response in Escherichia coli cells
por: Tan, Kang Wei, et al.
Publicado: (2015)

Genome maintenance functions of a putative Trypanosoma brucei translesion DNA polymerase include telomere association and a role in antigenic variation
por: Leal, Andrea Zurita, et al.
Publicado: (2020)

The catalytic function of the Rev1 dCMP transferase is required in a lesion-specific manner for translesion synthesis and base damage-induced mutagenesis
por: Zhou, Ying, et al.
Publicado: (2010)

Translesion DNA synthesis-assisted non-homologous end-joining of complex double-strand breaks prevents loss of DNA sequences in mammalian cells
por: Covo, Shay, et al.
Publicado: (2009)

DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8–2′-deoxyguanosine adduct of the dietary mutagen IQ in human cells
por: Bose, Arindam, et al.
Publicado: (2015)

Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing
por: Li, Jingzhen, et al.
Publicado: (2021)

Transcriptional mutagenesis reduces splicing fidelity in mammalian cells
por: Paredes, João A., et al.
Publicado: (2017)

Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins
por: Jiménez, Maddalen, et al.
Publicado: (2019)

MEN1 is a regulator of alternative splicing and prevents R-loop-induced genome instability through suppression of RNA polymerase II elongation
por: Jin, Bangming, et al.
Publicado: (2023)

RBM6 splicing factor promotes homologous recombination repair of double-strand breaks and modulates sensitivity to chemotherapeutic drugs
por: Machour, Feras E, et al.
Publicado: (2021)

Somatic CAG expansion in Huntington's disease is dependent on the MLH3 endonuclease domain, which can be excluded via splice redirection
por: Roy, Jennie C L, et al.
Publicado: (2021)

The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion
por: Rajesh, Changanamkandath, et al.
Publicado: (2011)

The RNA processing factors THRAP3 and BCLAF1 promote the DNA damage response through selective mRNA splicing and nuclear export
por: Vohhodina, Jekaterina, et al.
Publicado: (2017)

TRIM21 suppresses CHK1 activation by preferentially targeting CLASPIN for K63-linked ubiquitination
por: Zhu, Xuefei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n384ai3l8jipjuua1sppo217ve