Cargando…

In cell mutational interference mapping experiment (in cell MIME) identifies the 5′ polyadenylation signal as a dual regulator of HIV-1 genomic RNA production and packaging

Non-coding RNA regulatory elements are important for viral replication, making them promising targets for therapeutic intervention. However, regulatory RNA is challenging to detect and characterise using classical structure-function assays. Here, we present in cell Mutational Interference Mapping Ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Smyth, Redmond P, Smith, Maureen R, Jousset, Anne-Caroline, Despons, Laurence, Laumond, Géraldine, Decoville, Thomas, Cattenoz, Pierre, Moog, Christiane, Jossinet, Fabrice, Mougel, Marylène, Paillart, Jean-Christophe, von Kleist, Max, Marquet, Roland
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Methods Online
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961354/ https://www.ncbi.nlm.nih.gov/pubmed/29514260 http://dx.doi.org/10.1093/nar/gky152

Ejemplares similares

Translational regulation of APOBEC3G mRNA by Vif requires its 5′UTR and contributes to restoring HIV-1 infectivity
por: Guerrero, Santiago, et al.
Publicado: (2016)

HIV controls the selective packaging of genomic, spliced viral and cellular RNAs into virions through different mechanisms
por: Houzet, Laurent, et al.
Publicado: (2007)

Neutralizing Antibodies Inhibit HIV-1 Infection of Plasmacytoid Dendritic Cells by an FcγRIIa Independent Mechanism and Do Not Diminish Cytokines Production
por: Lederle, Alexandre, et al.
Publicado: (2014)

Mime in class and theatre
por: Marash, Jessie G.
Publicado: (1950)

Tomaszewski's mime theatre.
Publicado: (1975)

Non-neutralizing Antibodies Targeting the V1V2 Domain of HIV Exhibit Strong Antibody-Dependent Cell-mediated Cytotoxic Activity
por: Mayr, Luzia M., et al.
Publicado: (2017)

Distinct antibody profiles in HLA-B(∗)57(+), HLA-B(∗)57(−) HIV controllers and chronic progressors
por: Klingler, Jéromine, et al.
Publicado: (2022)

HIV-1 specifically encapsidates other nucleic acids than its genomic RNA
por: Didierlaurent, Ludovic, et al.
Publicado: (2009)

The Life-Cycle of the HIV-1 Gag–RNA Complex
por: Mailler, Elodie, et al.
Publicado: (2016)

Structural and Functional Motifs in Influenza Virus RNAs
por: Ferhadian, Damien, et al.
Publicado: (2018)

From Cells to Virus Particles: Quantitative Methods to Monitor RNA Packaging
por: Ferrer, Mireia, et al.
Publicado: (2016)

Data Model for Initiatives to Monitor Exposure to Antimicrobials (DataMIME)
por: Patel, Megan T., et al.
Publicado: (2018)

Protocol for project MIME: Motivation, inflammation, and Mood in Emerging Adults
por: Moriarity, Daniel P., et al.
Publicado: (2022)

Watch the Mime Carefully! A Refractory Interstitial Lung Disease
por: Graziano, Paolo, et al.
Publicado: (2022)

Requirements for nucleocapsid-mediated regulation of reverse transcription during the late steps of HIV-1 assembly
por: Racine, Pierre-Jean, et al.
Publicado: (2016)

A Rare Case of Tuberculosis with Sacrococcygeal Involvement Miming a Neoplasm
por: Osman, Walid, et al.
Publicado: (2016)

Exploring Highly Conserved Regions of SARS-CoV-2 Spike S2 Subunit as Targets for Fusion Inhibition Using Chimeric Proteins
por: Polo-Megías, Daniel, et al.
Publicado: (2022)

Characterization of the interaction between the HIV-1 Gag structural polyprotein and the cellular ribosomal protein L7 and its implication in viral nucleic acid remodeling
por: Mekdad, Hala El, et al.
Publicado: (2016)

Antibacterial Activities of Homemade Matrices Miming Essential Oils Compared to Commercial Ones
por: Oliveira Ribeiro, Sofia, et al.
Publicado: (2021)

Multimodality Imaging Assessment of Desmoid Tumors: The Great Mime in the Era of Multidisciplinary Teams
por: Simonetti, Igino, et al.
Publicado: (2022)

Structural maturation of the HIV-1 RNA 5’ untranslated region by Pr55(Gag) and its maturation products
por: Gilmer, Orian, et al.
Publicado: (2022)

Short- and long-range interactions in the HIV-1 5′ UTR regulate genome dimerization and packaging
por: Ye, Liqing, et al.
Publicado: (2022)

Chemical and Enzymatic Probing of Viral RNAs: From Infancy to Maturity and Beyond
por: Gilmer, Orian, et al.
Publicado: (2021)

8-Modified-2′-Deoxyadenosine Analogues Induce Delayed Polymerization Arrest during HIV-1 Reverse Transcription
por: Vivet-Boudou, Valérie, et al.
Publicado: (2011)

MoMuLV and HIV-1 Nucleocapsid Proteins Have a Common Role in Genomic RNA Packaging but Different in Late Reverse Transcription
por: Chamontin, Célia, et al.
Publicado: (2012)

Author Correction: Short- and long-range interactions in the HIV-1 5′ UTR regulate genome dimerization and packaging
por: Ye, Liqing, et al.
Publicado: (2023)

It's all in the mime: Actions speak louder than words when teaching the cranial nerves
por: Dickson, Kerry Ann, et al.
Publicado: (2015)

Segmental testicular infarction: Case series and brief literature review of a great mime
por: Palmisano, Franco, et al.
Publicado: (2019)

Amyloidβ Peptides in interaction with raft-mime model membranes: a neutron reflectivity insight
por: Rondelli, Valeria, et al.
Publicado: (2016)

Comprehensive microbiome causal mediation analysis using MiMed on user-friendly web interfaces
por: Jang, Hyojung, et al.
Publicado: (2023)

P04-36. HIV-1-speficic antibody dependant cellular cytotoxicity (ADCC) médiated by primary NK cells
por: Delaporte, M, et al.
Publicado: (2009)

Murine leukemia virus RNA dimerization is coupled to transcription and splicing processes
por: Maurel, Stéphan, et al.
Publicado: (2010)

The Great Mime: Three Cases of Melanoma with Carcinoid-Like and Paraganglioma-Like Pattern with Emphasis on Differential Diagnosis
por: Cazzato, Gerardo, et al.
Publicado: (2021)

PheMIME: An Interactive Web App and Knowledge Base for Phenome-Wide, Multi-Institutional Multimorbidity Analysis
por: Zhang, Siwei, et al.
Publicado: (2023)

P11-16. Transfer of HIV-1 from Langerhans and interstitial dendritic cells to T lymphocytes: protection mediated by antibodies?
por: Peressin, M, et al.
Publicado: (2009)

P04-29. HIV-1 neutralizing antibodies inhibit plasmacytoid dendritic cells infection
por: Lederle, A, et al.
Publicado: (2009)

Sequential disruption of SPLASH-identified vRNA–vRNA interactions challenges their role in influenza A virus genome packaging
por: Jakob, Celia, et al.
Publicado: (2023)

Hijacking of the Ubiquitin/Proteasome Pathway by the HIV Auxiliary Proteins
por: Seissler, Tanja, et al.
Publicado: (2017)

Encryption in a Windows Environment: EFS File, 802.1x Wireless, IPSec Transport, and S/MIME Exchange
por: Morimoto, Rand
Publicado: (2006)

Minimally Invasive Muscle Embedding (MIME) - A Novel Experimental Technique to Facilitate Donor-Cell-Mediated Myogenesis
por: Roche, Joseph A, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_ffuikbpo2gugb3s5d6or0e4pgi