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Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea
Hair cell (HC) loss is irreversible because only very limited HC regeneration has been observed in the adult mammalian cochlea. Wnt/β-catenin signaling regulates prosensory cell proliferation and differentiation during cochlear development, and Wnt activation promotes the proliferation of Lgr5+ coch...
Autores principales: | Zhang, Yanping, Guo, Luo, Lu, Xiaoling, Cheng, Cheng, Sun, Shan, Li, Wen, Zhao, Liping, Lai, Chuijin, Zhang, Shasha, Yu, Chenjie, Tang, Mingliang, Chen, Yan, Chai, Renjie, Li, Huawei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961437/ https://www.ncbi.nlm.nih.gov/pubmed/29867341 http://dx.doi.org/10.3389/fnmol.2018.00147 |
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