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Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging

In recent years, owing to unsatisfactory clinical imaging clarity and depths in the living body for early diagnosis and prognosis, novel imaging modalities with high bioimaging performance have been actively explored. The remarkable headway made in the second near-infrared region (NIR-II, 1000–1700...

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Detalles Bibliográficos
Autores principales: Ding, Feng, Zhan, Yibei, Lu, Xiaoju, Sun, Yao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961444/
https://www.ncbi.nlm.nih.gov/pubmed/29896378
http://dx.doi.org/10.1039/c8sc01153b
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author Ding, Feng
Zhan, Yibei
Lu, Xiaoju
Sun, Yao
author_facet Ding, Feng
Zhan, Yibei
Lu, Xiaoju
Sun, Yao
author_sort Ding, Feng
collection PubMed
description In recent years, owing to unsatisfactory clinical imaging clarity and depths in the living body for early diagnosis and prognosis, novel imaging modalities with high bioimaging performance have been actively explored. The remarkable headway made in the second near-infrared region (NIR-II, 1000–1700 nm) has promoted the development of biomedical imaging significantly. NIR-II fluorescence imaging possesses a number of merits which prevail over the traditional and NIR-I (400–900 nm) imaging modalities in fundamental research, such as reduced photon scattering, as well as auto-fluorescence and improved penetration depth. Functional probes for instant and precise feedback of in vivo information are at the core of this modality for superb imaging. Herein, we review the recently developed fluorophores including carbon nanotubes, organic small molecules, quantum dots, conjugated polymers and rare-earth-doped materials to present superior and multifunctionality of biomedical imaging in the NIR-II regions (1000–1700 nm).
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spelling pubmed-59614442018-06-12 Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging Ding, Feng Zhan, Yibei Lu, Xiaoju Sun, Yao Chem Sci Chemistry In recent years, owing to unsatisfactory clinical imaging clarity and depths in the living body for early diagnosis and prognosis, novel imaging modalities with high bioimaging performance have been actively explored. The remarkable headway made in the second near-infrared region (NIR-II, 1000–1700 nm) has promoted the development of biomedical imaging significantly. NIR-II fluorescence imaging possesses a number of merits which prevail over the traditional and NIR-I (400–900 nm) imaging modalities in fundamental research, such as reduced photon scattering, as well as auto-fluorescence and improved penetration depth. Functional probes for instant and precise feedback of in vivo information are at the core of this modality for superb imaging. Herein, we review the recently developed fluorophores including carbon nanotubes, organic small molecules, quantum dots, conjugated polymers and rare-earth-doped materials to present superior and multifunctionality of biomedical imaging in the NIR-II regions (1000–1700 nm). Royal Society of Chemistry 2018-04-24 /pmc/articles/PMC5961444/ /pubmed/29896378 http://dx.doi.org/10.1039/c8sc01153b Text en This journal is © The Royal Society of Chemistry 2018 http://creativecommons.org/licenses/by-nc/3.0/ This article is freely available. This article is licensed under a Creative Commons Attribution Non Commercial 3.0 Unported Licence (CC BY-NC 3.0)
spellingShingle Chemistry
Ding, Feng
Zhan, Yibei
Lu, Xiaoju
Sun, Yao
Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title_full Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title_fullStr Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title_full_unstemmed Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title_short Recent advances in near-infrared II fluorophores for multifunctional biomedical imaging
title_sort recent advances in near-infrared ii fluorophores for multifunctional biomedical imaging
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961444/
https://www.ncbi.nlm.nih.gov/pubmed/29896378
http://dx.doi.org/10.1039/c8sc01153b
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