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Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania

BACKGROUND: Human African trypanosomiasis (HAT) is one of the most complex parasitic diseases known to humankind. It usually occurs in endemic areas in Africa, but is occasionally detected in returning travelers and migrants in non-endemic countries. CASE PRESENTATION: In August 2017, a case of HAT...

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Autores principales: Liu, Qin, Chen, Xiao-Ling, Chen, Mu-Xin, Xie, Han-Guo, Liu, Qing, Chen, Zhu-Yun, Lin, Yao-Ying, Zheng, Hua, Chen, Jia-Xu, Zhang, Yi, Zhou, Xiao-Nong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961482/
https://www.ncbi.nlm.nih.gov/pubmed/29779491
http://dx.doi.org/10.1186/s40249-018-0432-5
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author Liu, Qin
Chen, Xiao-Ling
Chen, Mu-Xin
Xie, Han-Guo
Liu, Qing
Chen, Zhu-Yun
Lin, Yao-Ying
Zheng, Hua
Chen, Jia-Xu
Zhang, Yi
Zhou, Xiao-Nong
author_facet Liu, Qin
Chen, Xiao-Ling
Chen, Mu-Xin
Xie, Han-Guo
Liu, Qing
Chen, Zhu-Yun
Lin, Yao-Ying
Zheng, Hua
Chen, Jia-Xu
Zhang, Yi
Zhou, Xiao-Nong
author_sort Liu, Qin
collection PubMed
description BACKGROUND: Human African trypanosomiasis (HAT) is one of the most complex parasitic diseases known to humankind. It usually occurs in endemic areas in Africa, but is occasionally detected in returning travelers and migrants in non-endemic countries. CASE PRESENTATION: In August 2017, a case of HAT was diagnosed in China in a traveler returning from the Masai Mara area in Kenya and the Serengeti area in Tanzania. The traveler visited Africa from 23 July to 5 August, 2017. Upon return to China, she developed a fever (on 8 August), and Trypanosoma brucei rhodesiense infection was confirmed by laboratory tests (on 14 August) including observation of parasites in blood films and by polymerase chain reaction. She was treated with pentamidine followed by suramin, and recovered 1 month later. CONCLUSIONS: This is the first imported rhodesiense HAT case reported in China. This case alerts clinical and public health workers to be aware of HAT in travelers, and expatriates and migrants who have visited at-risk areas in Africa. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40249-018-0432-5) contains supplementary material, which is available to authorized users.
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spelling pubmed-59614822018-06-25 Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania Liu, Qin Chen, Xiao-Ling Chen, Mu-Xin Xie, Han-Guo Liu, Qing Chen, Zhu-Yun Lin, Yao-Ying Zheng, Hua Chen, Jia-Xu Zhang, Yi Zhou, Xiao-Nong Infect Dis Poverty Case Report BACKGROUND: Human African trypanosomiasis (HAT) is one of the most complex parasitic diseases known to humankind. It usually occurs in endemic areas in Africa, but is occasionally detected in returning travelers and migrants in non-endemic countries. CASE PRESENTATION: In August 2017, a case of HAT was diagnosed in China in a traveler returning from the Masai Mara area in Kenya and the Serengeti area in Tanzania. The traveler visited Africa from 23 July to 5 August, 2017. Upon return to China, she developed a fever (on 8 August), and Trypanosoma brucei rhodesiense infection was confirmed by laboratory tests (on 14 August) including observation of parasites in blood films and by polymerase chain reaction. She was treated with pentamidine followed by suramin, and recovered 1 month later. CONCLUSIONS: This is the first imported rhodesiense HAT case reported in China. This case alerts clinical and public health workers to be aware of HAT in travelers, and expatriates and migrants who have visited at-risk areas in Africa. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s40249-018-0432-5) contains supplementary material, which is available to authorized users. BioMed Central 2018-05-21 /pmc/articles/PMC5961482/ /pubmed/29779491 http://dx.doi.org/10.1186/s40249-018-0432-5 Text en © The Author(s). 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Liu, Qin
Chen, Xiao-Ling
Chen, Mu-Xin
Xie, Han-Guo
Liu, Qing
Chen, Zhu-Yun
Lin, Yao-Ying
Zheng, Hua
Chen, Jia-Xu
Zhang, Yi
Zhou, Xiao-Nong
Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title_full Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title_fullStr Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title_full_unstemmed Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title_short Trypanosoma brucei rhodesiense infection in a Chinese traveler returning from the Serengeti National Park in Tanzania
title_sort trypanosoma brucei rhodesiense infection in a chinese traveler returning from the serengeti national park in tanzania
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961482/
https://www.ncbi.nlm.nih.gov/pubmed/29779491
http://dx.doi.org/10.1186/s40249-018-0432-5
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