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Newly developed controlled release subcutaneous formulation for tramadol hydrochloride
This study presents a drug delivery system of poly (Ɛ-caprolactone) (PCL) ribbons to optimize the pharmaceutical action of tramadol for the first time according to our knowledge. PCL ribbons were fabricated and loaded with tramadol HCl. Ribbons were prepared by slip casting technique and coated with...
Autores principales: | Mabrouk, Mostafa, Beherei, Hanan H., ElShebiney, Shaimaa, Tanaka, Masaru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961623/ https://www.ncbi.nlm.nih.gov/pubmed/29844731 http://dx.doi.org/10.1016/j.jsps.2018.01.014 |
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