Cargando…

Characterization of forced degradation products of toloxatone by LC-ESI-MS/MS

Forced degradation of toloxatone in solutions under basic, acidic, neutral, photo UV–VIS, photo UVC and oxidative stress conditions was investigated and structural elucidation of its degradation products was performed with the use of UHPLC system coupled ESI-Q-TOF mass spectrometer. Eight degradatio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Skibiński, Robert, Trawiński, Jakub, Komsta, Łukasz, Murzec, Diana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961754/ https://www.ncbi.nlm.nih.gov/pubmed/29844717 http://dx.doi.org/10.1016/j.jsps.2018.02.012

Ejemplares similares

Multivariate Chemometric Comparison of Forced Degradation and Electrochemical Oxidation LC–MS Profiles of Maraviroc
por: Wroński, Michał, et al.
Publicado: (2023)

Forced Degradation Behaviour of Fluphenazine Hydrochloride by LC and Characterization of its Oxidative Degradation Product by LC–MS/MS
por: Thummar, Kashyap N., et al.
Publicado: (2015)

Photodegradation Study of Sertindole by UHPLC-ESI-Q-TOF and Influence of Some Metal Oxide Excipients on the Degradation Process
por: Trawiński, Jakub, et al.
Publicado: (2019)

LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
por: Tiwari, Ravi N., et al.
Publicado: (2015)

LC-ESI-QTOF-MS/MS Characterization of Seaweed Phenolics and Their Antioxidant Potential
por: Zhong, Biming, et al.
Publicado: (2020)

LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol
por: Rakibe, Uday, et al.
Publicado: (2018)

Characterization of the Oxidative Degradation Product of Darunavir by LC-MS/MS
por: Yamjala, Karthik, et al.
Publicado: (2015)

Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS
por: Joshi, Payal, et al.
Publicado: (2011)

Characterization of Phase I Hepatic Metabolites of Anti-Premature Ejaculation Drug Dapoxetine by UHPLC-ESI-Q-TOF
por: Skibiński, Robert, et al.
Publicado: (2021)

Phytochemical Analysis of Pfaffia glomerata Inflorescences by LC-ESI-MS/MS
por: Felipe, Daniele F., et al.
Publicado: (2014)

Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS
por: Attwa, Mohamed W., et al.
Publicado: (2018)

Enhanced LC-ESI-MS/MS Sensitivity by Cationic Derivatization of Organophosphorus Acids
por: Shamai Yamin, Tamar, et al.
Publicado: (2023)

Characterization of Bacteriophage Peptides of Pathogenic Streptococcus by LC-ESI-MS/MS: Bacteriophage Phylogenomics and Their Relationship to Their Host
por: Abril, Ana G., et al.
Publicado: (2020)

Colchicine measurement using LC-MS/MS with ESI in serum with liquid liquid extraction
por: Gul, H, et al.
Publicado: (2015)

Identification of lipopeptides in Bacillus megaterium by two-step ultrafiltration and LC–ESI–MS/MS
por: Ma, Yunxiao, et al.
Publicado: (2016)

A semi-virtual two dimensional gel electrophoresis: IF–ESI LC-MS/MS
por: Naryzhny, Stanislav, et al.
Publicado: (2017)

LC-ESI-MS/MS Alkaloidal Profiling and Biological Investigation of Cleistocactus winteri Stems
por: Mina, Suzan Adib, et al.
Publicado: (2020)

The Quality Assessment of Commercial Lycium Berries Using LC-ESI-MS/MS and Chemometrics
por: Jarouche, Mariam, et al.
Publicado: (2019)

LC-DAD–ESI-MS/MS and NMR Analysis of Conifer Wood Specialized Metabolites
por: Patyra, Andrzej, et al.
Publicado: (2022)

Analysis of the Main Nucleosides in Cordyceps Sinensis by LC/ESI-MS
por: Xie, Jian-Wei, et al.
Publicado: (2010)

Phytochemical Diversity in Rhizomes of Three Reynoutria Species and their Antioxidant Activity Correlations Elucidated by LC-ESI-MS/MS Analysis
por: Nawrot-Hadzik, Izabela, et al.
Publicado: (2019)

Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic study
por: Ponnuru, Venkata Suresh, et al.
Publicado: (2012)

Effect of Casein Hydrolysates on Intestinal Cell Migration and Their Peptide Profiles by LC-ESI/MS/MS
por: Nielsen, Søren D., et al.
Publicado: (2019)

Structure Determination of Felodipine Photoproducts in UV-Irradiated Medicines Using ESI-LC/MS/MS
por: Kawabata, Kohei, et al.
Publicado: (2023)

Conocarpus lancifolius (Combretaceae): Pharmacological Effects, LC-ESI-MS/MS Profiling and In Silico Attributes
por: Khurm, Muhammad, et al.
Publicado: (2023)

LC-ESI-MS/MS Characterization of Concentrated Polyphenolic Fractions from Rhododendron luteum and Their Anti-Inflammatory and Antioxidant Activities
por: Łyko, Lena, et al.
Publicado: (2022)

Characterization of Nucleosides and Nucleobases in Natural Cordyceps by HILIC–ESI/TOF/MS and HILIC–ESI/MS
por: Zhao, Heng-Qiang, et al.
Publicado: (2013)

Comparison of EI-GC-MS/MS, APCI-LC-MS/MS, and ESI-LC-MS/MS for the Simultaneous Analysis of Nine Nitrosamines Eluted from Synthetic Resins into Artificial Saliva and Health Risk Assessment
por: Kim, Hyungsoo, et al.
Publicado: (2021)

LC-ESI-MS/MS reveals the formation of reactive intermediates in brigatinib metabolism: elucidation of bioactivation pathways
por: Kadi, Adnan A., et al.
Publicado: (2018)

Absolute quantification of endogenous angiotensin II levels in human plasma using ESI-LC-MS/MS
por: Schulz, Anna, et al.
Publicado: (2014)

Comparison of ESI– and APCI–LC–MS/MS methods: A case study of levonorgestrel in human plasma()
por: Wang, Rulin, et al.
Publicado: (2016)

Simultaneous determination of amlodipine, valsartan and hydrochlorothiazide by LC–ESI-MS/MS and its application to pharmacokinetics in rats
por: Gadepalli, Shankar Ganesh, et al.
Publicado: (2014)

Fast LC-ESI-MS/MS analysis and influence of sampling conditions for gut metabolites in plasma and serum
por: van der Laan, Tom, et al.
Publicado: (2019)

LC-ESI/MS/MS analysis of neonicotinoids in urine of very low birth weight infants at birth
por: Ichikawa, Go, et al.
Publicado: (2019)

LC-ESI-MS/MS Identification of Biologically Active Phenolics in Different Extracts of Alchemilla acutiloba Opiz
por: Dos Santos Szewczyk, Katarzyna, et al.
Publicado: (2022)

Proteomic Characterization of Bacteriophage Peptides from the Mastitis Producer Staphylococcus aureus by LC-ESI-MS/MS and the Bacteriophage Phylogenomic Analysis
por: Abril, Ana G., et al.
Publicado: (2021)

The LC-QTOF-MS/MS analysis of acid degradation products of Rifaximin, an antibiotic
por: Yaseen, Saima Baig, et al.
Publicado: (2022)

Comprehensive Metabolite Profiling of Chemlali Olive Tree Root Extracts Using LC-ESI-QTOF-MS/MS, Their Cytotoxicity, and Antiviral Assessment
por: Toumi, Karim, et al.
Publicado: (2023)

Study of forced degradation behavior of pramlintide acetate by HPLC and LC–MS
por: Yuan, Yu, et al.
Publicado: (2017)

Identification and Characterization of Hydrolytic Degradation Products of Cefditoren Pivoxil using LC and LC-MS/TOF
por: Gawande, V. T., et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ido2n2ph7e53tqtmn4etmfklhl