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Memory-Augmented Active Deep Learning for Identifying Relations Between Distant Medical Concepts in Electroencephalography Reports

The automatic identification of relations between medical concepts in a large corpus of Electroencephalography (EEG) reports is an important step in the development of an EEG-specific patient cohort retrieval system as well as in the acquisition of EEG-specific knowledge from this corpus. EEG-specif...

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Detalles Bibliográficos
Autores principales: Maldonado, Ramon, Goodwin, Travis R., Harabagiu, Sanda M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961777/
https://www.ncbi.nlm.nih.gov/pubmed/29888063
Descripción
Sumario:The automatic identification of relations between medical concepts in a large corpus of Electroencephalography (EEG) reports is an important step in the development of an EEG-specific patient cohort retrieval system as well as in the acquisition of EEG-specific knowledge from this corpus. EEG-specific relations involve medical concepts that are not typically mentioned in the same sentence or even the same section of a report, thus requiring extraction techniques that can handle such long-distance dependencies. To address this challenge, we present a novel frame work which combines the advantages of a deep learning framework employing Dynamic Relational Memory (DRM) with active learning. While DRM enables the prediction of long-distance relations, active learning provides a mechanism for accurately identifying relations with minimal training data, obtaining an 5-fold cross validationF1 score of 0.7475 on a set of 140 EEG reports selected with active learning. The results obtained with our novel framework show great promise.