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GNOMICS: A one-stop shop for biomedical and genomic data

The World Wide Web is an indispensable tool for biomedical researchers who are striving to understand the molecular basis of phenotype. However, it presents challenges in the form of proliferation of data resources, with heterogeneity ranging from their content to functionality to interfaces. This o...

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Detalles Bibliográficos
Autores principales: Kronk, Charles J., Jegga, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Informatics Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961829/
https://www.ncbi.nlm.nih.gov/pubmed/29888054
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author Kronk, Charles J.
Jegga, Anil
author_facet Kronk, Charles J.
Jegga, Anil
author_sort Kronk, Charles J.
collection PubMed
description The World Wide Web is an indispensable tool for biomedical researchers who are striving to understand the molecular basis of phenotype. However, it presents challenges in the form of proliferation of data resources, with heterogeneity ranging from their content to functionality to interfaces. This often frustrates researchers who must visit multiple sites, become familiar with their interfaces, and learn how to use them to extract knowledge. Even then, one may never feel sure that they have tracked down all needed information. We envision addressing this challenge with GNOMICS (Genomic Nomenclature Omnibus and Multifaceted Informatics and Computational Suite), a suite with both a programmatic interface and a GUI. GNOMICS allows for extensible biomedical functionality, including identifier conversion, pathway enrichment, sequence alignment, and reference gathering, among others. It combines usage of other biological and chemical database application programming interfaces (APIs) to deliver uniform data which can be further manipulated and parsed.
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spelling pubmed-59618292018-06-08 GNOMICS: A one-stop shop for biomedical and genomic data Kronk, Charles J. Jegga, Anil AMIA Jt Summits Transl Sci Proc Articles The World Wide Web is an indispensable tool for biomedical researchers who are striving to understand the molecular basis of phenotype. However, it presents challenges in the form of proliferation of data resources, with heterogeneity ranging from their content to functionality to interfaces. This often frustrates researchers who must visit multiple sites, become familiar with their interfaces, and learn how to use them to extract knowledge. Even then, one may never feel sure that they have tracked down all needed information. We envision addressing this challenge with GNOMICS (Genomic Nomenclature Omnibus and Multifaceted Informatics and Computational Suite), a suite with both a programmatic interface and a GUI. GNOMICS allows for extensible biomedical functionality, including identifier conversion, pathway enrichment, sequence alignment, and reference gathering, among others. It combines usage of other biological and chemical database application programming interfaces (APIs) to deliver uniform data which can be further manipulated and parsed. American Medical Informatics Association 2018-05-18 /pmc/articles/PMC5961829/ /pubmed/29888054 Text en ©2018 AMIA - All rights reserved. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose
spellingShingle Articles
Kronk, Charles J.
Jegga, Anil
GNOMICS: A one-stop shop for biomedical and genomic data
title GNOMICS: A one-stop shop for biomedical and genomic data
title_full GNOMICS: A one-stop shop for biomedical and genomic data
title_fullStr GNOMICS: A one-stop shop for biomedical and genomic data
title_full_unstemmed GNOMICS: A one-stop shop for biomedical and genomic data
title_short GNOMICS: A one-stop shop for biomedical and genomic data
title_sort gnomics: a one-stop shop for biomedical and genomic data
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961829/
https://www.ncbi.nlm.nih.gov/pubmed/29888054
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