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A novel mechanism for regulation of the type I IFN response by herpesvirus deconjugases

Upon infection, viral nucleic acids are recognized by germline-encoded pattern-recognition receptors (PRRs), and cytosolic retinoic acid-inducible gene I (RIG-I)-like helicases (RLHs) that initiate signaling pathways resulting in the production of type I IFN and pro-inflammatory cytokines. Binding o...

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Detalles Bibliográficos
Autores principales: Gupta, Soham, Ylä-Anttila, Päivi, Masucci, Maria G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5961920/
https://www.ncbi.nlm.nih.gov/pubmed/29799549
http://dx.doi.org/10.15698/mic2018.05.633