Structural insights on the efficient catalysis of hydroperoxide reduction by Ohr: Crystallographic and molecular dynamics approaches

Organic hydroperoxide resistance (Ohr) enzymes are highly efficient Cys-based peroxidases that play central roles in bacterial response to fatty acid hydroperoxides and peroxynitrite, two oxidants that are generated during host-pathogen interactions. In the active site of Ohr proteins, the conserved...

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Detalles Bibliográficos
Autores principales: Piccirillo, Erika, Alegria, Thiago G. P., Discola, Karen F., Cussiol, José R. R., Domingos, Renato M., de Oliveira, Marcos A., de Rezende, Leandro, Netto, Luis E. S., Amaral, Antonia T-do
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962072/
https://www.ncbi.nlm.nih.gov/pubmed/29782551
http://dx.doi.org/10.1371/journal.pone.0196918

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