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Rosmarinic acid is a novel inhibitor for Hepatitis B virus replication targeting viral epsilon RNA-polymerase interaction
Current therapeutics for hepatitis B virus (HBV) patients such as nucleoside analogs (NAs) are effective; however, new antiviral drugs against HBV are still desired. Since the interaction between the epsilon (ε) sequence of HBV pregenomic RNA and viral polymerase (Pol) is a key step in the HBV repli...
Autores principales: | Tsukamoto, Yuta, Ikeda, Sotaro, Uwai, Koji, Taguchi, Riho, Chayama, Kazuaki, Sakaguchi, Takemasa, Narita, Ryo, Yao, Wan-Ling, Takeuchi, Fumihiko, Otakaki, Yukie, Watashi, Koichi, Wakita, Takaji, Kato, Hiroki, Fujita, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962091/ https://www.ncbi.nlm.nih.gov/pubmed/29782545 http://dx.doi.org/10.1371/journal.pone.0197664 |
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