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The HSV-1 mechanisms of cell-to-cell spread and fusion are critically dependent on host PTP1B

All herpesviruses have mechanisms for passing through cell junctions, which exclude neutralizing antibodies and offer a clear path to neighboring, uninfected cells. In the case of herpes simplex virus type 1 (HSV-1), direct cell-to-cell transmission takes place between epithelial cells and sensory n...

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Detalles Bibliográficos
Autores principales: Carmichael, Jillian C., Yokota, Hiroki, Craven, Rebecca C., Schmitt, Anthony, Wills, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962101/
https://www.ncbi.nlm.nih.gov/pubmed/29742155
http://dx.doi.org/10.1371/journal.ppat.1007054