SHOC1 is a ERCC4-(HhH)(2)-like protein, integral to the formation of crossover recombination intermediates during mammalian meiosis

Chromosome segregation errors during meiosis result in the formation of aneuploid gametes and are the leading cause of pregnancy loss and birth defects in humans. Proper chromosome segregation requires pairwise associations of maternal and paternal homologous chromosomes. Chiasmata, which are the cy...

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Detalles Bibliográficos
Autores principales: Guiraldelli, Michel F., Felberg, Anna, Almeida, Luciana P., Parikh, Aniruddha, de Castro, Rodrigo O., Pezza, Roberto J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962103/
https://www.ncbi.nlm.nih.gov/pubmed/29742103
http://dx.doi.org/10.1371/journal.pgen.1007381

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