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Bacillus Calmette–Guérin and anti-PD-L1 combination therapy boosts immune response against bladder cancer
BACKGROUND: Programmed death-ligand 1 (PD-L1) is a critical immune checkpoint molecule which promotes immunosuppression by binding to PD-1 on T-cells in tumor immunity. We have previously identified that activation of toll like receptor 4 (TLR-4), which serves an important role in the induction of a...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove Medical Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962256/ https://www.ncbi.nlm.nih.gov/pubmed/29844686 http://dx.doi.org/10.2147/OTT.S165840 |