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RIP1 regulates TNF-α-mediated lymphangiogenesis and lymphatic metastasis in gallbladder cancer by modulating the NF-κB-VEGF-C pathway

BACKGROUND: Tumor necrosis factor alpha (TNF-α) enhances lymphangiogenesis in gallbladder carcinoma (GBC) via activation of nuclear factor (NF-κB)-dependent vascular endothelial growth factor-C (VEGF-C). Receptor-interacting protein 1 (RIP1) is a multifunctional protein in the TNF-α signaling pathwa...

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Detalles Bibliográficos
Autores principales: Li, Cheng-Zong, Jiang, Xiao-Jie, Lin, Bin, Hong, Hai-Jie, Zhu, Si-Yuan, Jiang, Lei, Wang, Xiao-Qian, Tang, Nan-Hong, She, Fei-Fei, Chen, Yan-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962258/
https://www.ncbi.nlm.nih.gov/pubmed/29844685
http://dx.doi.org/10.2147/OTT.S159026