Novel peptide GX1 inhibits angiogenesis by specifically binding to transglutaminase-2 in the tumorous endothelial cells of gastric cancer

The clinical application of GX1, an optimal gastric cancer (GC) targeting peptide, is greatly limited because its receptor in the GC vasculature is unknown. In this study, we screened the candidate receptor of GX1, transglutaminase-2(TGM2), by co-immunoprecipitation (co-IP) combined with mass spectr...

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Detalles Bibliográficos
Autores principales: Lei, Zhijie, Chai, Na, Tian, Miaomiao, Zhang, Ying, Wang, Guodong, Liu, Jian, Tian, Zuhong, Yi, Xiaofang, Chen, Di, Li, Xiaowei, Yu, Pengfei, Hu, Hao, Xu, Bing, Jian, Chao, Bian, Zhenyuan, Guo, Hao, Wang, Jinpeng, Peng, Shiming, Nie, Yongzhan, Huang, Niu, Hu, Sijun, Wu, Kaichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962530/
https://www.ncbi.nlm.nih.gov/pubmed/29785022
http://dx.doi.org/10.1038/s41419-018-0594-x

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