Genome-wide association study identified new susceptible genetic variants in HLA class I region for hepatitis B virus-related hepatocellular carcinoma

We have performed a genome-wide association study (GWAS) including 473 Japanese HBV (hepatitis B virus)-positive HCC (hepatocellular carcinoma) patients and 516 HBV carriers including chronic hepatitis and asymptomatic carrier individuals to identify new host genetic factors associated with HBV-deri...

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Autores principales: Sawai, Hiromi, Nishida, Nao, Khor, Seik-Soon, Honda, Masao, Sugiyama, Masaya, Baba, Natsumi, Yamada, Kayoko, Sawada, Norie, Tsugane, Shoichiro, Koike, Kazuhiko, Kondo, Yuji, Yatsuhashi, Hiroshi, Nagaoka, Shinya, Taketomi, Akinobu, Fukai, Moto, Kurosaki, Masayuki, Izumi, Namiki, Kang, Jong-Hon, Murata, Kazumoto, Hino, Keisuke, Nishina, Sohji, Matsumoto, Akihiro, Tanaka, Eiji, Sakamoto, Naoya, Ogawa, Koji, Yamamoto, Kazuhide, Tamori, Akihiro, Yokosuka, Osamu, Kanda, Tatsuo, Sakaida, Isao, Itoh, Yoshito, Eguchi, Yuichiro, Oeda, Satoshi, Mochida, Satoshi, Yuen, Man-Fung, Seto, Wai-Kay, Poovorawan, Yong, Posuwan, Nawarat, Mizokami, Masashi, Tokunaga, Katsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962604/
https://www.ncbi.nlm.nih.gov/pubmed/29784950
http://dx.doi.org/10.1038/s41598-018-26217-7

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