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IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View

In this historical perspective, written in honor of Dr. William E. Paul, we describe the initial discovery of one of the dominant substrates for tyrosine phosphorylation stimulated by IL-4. We further describe how this “IL-4-induced phosphorylated substrate” (4PS) was characterized as a member of th...

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Detalles Bibliográficos
Autores principales:	Keegan, Achsah D., Zamorano, Jose, Keselman, Aleksander, Heller, Nicola M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962649/ https://www.ncbi.nlm.nih.gov/pubmed/29868002 http://dx.doi.org/10.3389/fimmu.2018.01037

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