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Phosphatidyl Inositol 3 Kinase-Gamma Balances Antiviral and Inflammatory Responses During Influenza A H1N1 Infection: From Murine Model to Genetic Association in Patients

Influenza A virus (IAV) infection causes severe pulmonary disease characterized by intense leukocyte infiltration. Phosphoinositide-3 kinases (PI3Ks) are central signaling enzymes, involved in cell growth, survival, and migration. Class IB PI3K or phosphatidyl inositol 3 kinase-gamma (PI3Kγ), mainly...

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Detalles Bibliográficos
Autores principales:	Garcia, Cristiana C., Tavares, Luciana P., Dias, Ana Carolina F., Kehdy, Fernanda, Alvarado-Arnez, Lucia Elena, Queiroz-Junior, Celso M., Galvão, Izabela, Lima, Braulio H., Matos, Aline R., Gonçalves, Ana Paula F., Soriani, Frederico M., Moraes, Milton O., Marques, João T., Siqueira, Marilda M., Machado, Alexandre M. V., Sousa, Lirlândia P., Russo, Remo C., Teixeira, Mauro M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962662/ https://www.ncbi.nlm.nih.gov/pubmed/29867955 http://dx.doi.org/10.3389/fimmu.2018.00975

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