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Betulinic Acid Exerts Cytotoxic Activity Against Multidrug-Resistant Tumor Cells via Targeting Autocrine Motility Factor Receptor (AMFR)

Betulinic acid (BetA) is a naturally occurring pentacyclic triterpene isolated from the outer bark of white-barked birch trees and many other medicinal plants. Here, we studied betulinic acid's cytotoxic activity against drug-resistant tumor cell lines. P-glycoprotein (MDR1/ABCB1) and BCRP (ABC...

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Detalles Bibliográficos
Autores principales:	Saeed, Mohamed E. M., Mahmoud, Nuha, Sugimoto, Yoshikazu, Efferth, Thomas, Abdel-Aziz, Heba
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962668/ https://www.ncbi.nlm.nih.gov/pubmed/29867487 http://dx.doi.org/10.3389/fphar.2018.00481

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