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A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis

Although it is largely unknown how diet might modulate rheumatoid arthritis (RA), dietary interventions, including so-called “low-carbohydrate” diets, may be considered for RA patients because of the high incidence of cardiovascular comorbidity. However, it has been shown that restriction or skewed...

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Autor principal: Masuko, Kayo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962728/
https://www.ncbi.nlm.nih.gov/pubmed/29868593
http://dx.doi.org/10.3389/fmed.2018.00141
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author Masuko, Kayo
author_facet Masuko, Kayo
author_sort Masuko, Kayo
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description Although it is largely unknown how diet might modulate rheumatoid arthritis (RA), dietary interventions, including so-called “low-carbohydrate” diets, may be considered for RA patients because of the high incidence of cardiovascular comorbidity. However, it has been shown that restriction or skewed intake of particular nutrient may alter the components of the intestinal flora. Changes to the gut microbiota or dysbiosis may be relevant to the pathogenesis of RA because the gut microbiota is reported to regulate the T cell phenotype and T cell-mediated immunity. RA patients should be advised that a balanced diet that includes appropriate amounts of carbohydrate, especially dietary fiber, is important for maintaining the symbiosis of intestinal flora, which could be beneficial for preventing autoimmunity. The review attempts to focus current findings regarding the suggested relationship between diet-derived carbohydrate, gut microbiota, and the pathogenesis of RA.
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spelling pubmed-59627282018-06-04 A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis Masuko, Kayo Front Med (Lausanne) Medicine Although it is largely unknown how diet might modulate rheumatoid arthritis (RA), dietary interventions, including so-called “low-carbohydrate” diets, may be considered for RA patients because of the high incidence of cardiovascular comorbidity. However, it has been shown that restriction or skewed intake of particular nutrient may alter the components of the intestinal flora. Changes to the gut microbiota or dysbiosis may be relevant to the pathogenesis of RA because the gut microbiota is reported to regulate the T cell phenotype and T cell-mediated immunity. RA patients should be advised that a balanced diet that includes appropriate amounts of carbohydrate, especially dietary fiber, is important for maintaining the symbiosis of intestinal flora, which could be beneficial for preventing autoimmunity. The review attempts to focus current findings regarding the suggested relationship between diet-derived carbohydrate, gut microbiota, and the pathogenesis of RA. Frontiers Media S.A. 2018-05-15 /pmc/articles/PMC5962728/ /pubmed/29868593 http://dx.doi.org/10.3389/fmed.2018.00141 Text en Copyright © 2018 Masuko. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Masuko, Kayo
A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title_full A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title_fullStr A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title_full_unstemmed A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title_short A Potential Benefit of “Balanced Diet” for Rheumatoid Arthritis
title_sort potential benefit of “balanced diet” for rheumatoid arthritis
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962728/
https://www.ncbi.nlm.nih.gov/pubmed/29868593
http://dx.doi.org/10.3389/fmed.2018.00141
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