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Activation of FXR promotes intestinal metaplasia of gastric cells via SHP-dependent upregulation of the expression of CDX2

Gastric intestinal metaplasia (IM) induced by bile acid is a precancerous lesion of gastric adenocarcinoma and is associated with the expression of caudal-related homeobox 2 (CDX2). In the present study, the role of farnesoid X receptor (FXR) on the regulation of CDX2 in gastric cells was investigat...

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Detalles Bibliográficos
Autores principales:	Zhou, Haining, Ni, Zhen, Li, Ting, Su, Linna, Zhang, Lianfeng, Liu, Na, Shi, Yongquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962842/ https://www.ncbi.nlm.nih.gov/pubmed/29849798 http://dx.doi.org/10.3892/ol.2018.8342

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