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Quantification of Bioorthogonal Stability in Immune Phagocytes Using Flow Cytometry Reveals Rapid Degradation of Strained Alkynes
[Image: see text] One of the areas in which bioorthogonal chemistry—chemistry performed inside a cell or organism—has become of pivotal importance is in the study of host–pathogen interactions. The incorporation of bioorthogonal groups into the cell wall or proteome of intracellular pathogens has al...
Autores principales: | Bakkum, Thomas, van Leeuwen, Tyrza, Sarris, Alexi J. C., van Elsland, Daphne M., Poulcharidis, Dimitrios, Overkleeft, Herman S., van Kasteren, Sander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2018
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962927/ https://www.ncbi.nlm.nih.gov/pubmed/29693370 http://dx.doi.org/10.1021/acschembio.8b00355 |
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