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Neurofibromin Deficiency Induces Endothelial Cell Proliferation and Retinal Neovascularization
PURPOSE: Neurofibromatosis type 1 (NF1) is the result of inherited mutations in the NF1 tumor suppressor gene, which encodes the protein neurofibromin. Eye manifestations are common in NF1 with recent reports describing a vascular dysplasia in the retina and choroid. Common features of NF1 retinopat...
Autores principales: | Zhang, Hanfang, Hudson, Farlyn Z., Xu, Zhimin, Tritz, Rebekah, Rojas, Modesto, Patel, Chintan, Haigh, Stephen B., Bordán, Zsuzsanna, Ingram, David A., Fulton, David J., Weintraub, Neal L., Caldwell, Ruth B., Stansfield, Brian K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963003/ https://www.ncbi.nlm.nih.gov/pubmed/29847659 http://dx.doi.org/10.1167/iovs.17-22588 |
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