Cargando…
A small molecule p53 activator attenuates Fanconi anemia leukemic stem cell proliferation
Although p53 mutations are common in solid tumors, such mutations are found at a lower frequency in hematologic malignancies. In the genetic disorder Fanconi anemia (FA), p53 has been proposed as an important pathophysiological factor for two important hematologic hallmarks of the disease: bone marr...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5963145/ https://www.ncbi.nlm.nih.gov/pubmed/29784053 http://dx.doi.org/10.1186/s13287-018-0882-5 |